New Bioinspired Membrane Made of a Biological Ion Channel Confined into the Cylindrical Nanopore of a Solid-State Polymer. Auteur(s): Balme Sébastien, Janot Jean-Marc, Berardo L., Henn F., Bonhenry Daniel, Kraszewski Sebastian, Picaud Fabien, Ramseyer Christophe (Article) Publié: Nano Letters, vol. 11 p.712-716 (2011) Ref HAL: hal-00555288_v1 PMID 21174453 DOI: 10.1021/nl103841m WoS: 000287049100068 Exporter : BibTex | endNote 46 Citations Résumé: A hybrid nanoporous membrane made of a solid-state polymeric thin film in which an ion channel is confined is realized. The primary and extremely encouraging results obtained by confocal fluorescence spectroscopy and ion diffusion measurement demonstrate respectively that (i) the considered ion channel, that is, Gramicidin-A, can be confined selectively inside the nanopores and (ii) the ionic permeability of the membrane is enhanced. Atomistic molecular simulations are also reported and fruitfully compared to the experimental findings. |