Sommaire:

Cells and tissues in many contexts are electrically polarized. In this work, we develop a three-dimensional electrohydraulic model that simultaneously solves for the electric potential, ion concentration, and hydrodynamic flows and stresses inside and outside a spherical water-filled cavity enclosed by an epithelium. We analyze two sources of electric asymmetry in the system: (i) heterogeneous ion transporter along the surface of the sphere and (ii) organoid in an external electric field. We show that inhomogeneous ion transport leads to an organ-scale electric current and water flux. Consistent with recent experimental observation we find that a constant electric field leads to isotropic swelling of the organ. Rejoindre Zoom Réunion https://umontpellier-fr.zoom.us/j/93456294768?pwd=VWFzOGk4RUhHaG1DVE9YQ3Z1dmNkdz09 ID de réunion: 934 5629 4768 Code secret: 052645

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