Sommaire:

The Twistable Wormlike chain (TWLC) is considered a standard model of DNA mechanics. Although this model captures some of the essential features observed in single molecule experiments, it is incomplete as it neglects an important interaction term which couples twist and bending degrees of freedom. Such twist-bend coupling follows from simple symmetry arguments
about the structure of the double helix. In this talk we will review some recent results showing how twist-bend coupling influences the structure and fluctuations of DNA. Our analysis is extended to the high deformation regime which is governed by interactions that go beyond linear elasticity, which will be briefly discussed.

Pour plus d'informations, merci de contacter Walter J.-C.