Accueil >
Production scientifique
(218) Production(s) de GERGELY C.
|
|
Insights on the facet specific adsorption of amino acids and peptides towards platinum.
Auteur(s): Ramakrishnan S., Martin Fernandez M., Cloitre T., Firlej L., Cuisinier Frédéric J. G., Gergely C.
(Article) Publié:
Journal Of Chemical Information And Modeling, vol. p.10.1021/ci400630d (2013)
Ref HAL: hal-00934304_v1
PMID 24289530
DOI: 10.1021/ci400630d
WoS: 000329137700017
Exporter : BibTex | endNote
17 Citations
Résumé: Engineering shape-controlled bionanomaterials requires comprehensive understanding of interactions between biomolecules and inorganic surfaces. We explore the origin of facet-selective binding of peptides adsorbed onto Pt(100) and Pt(111) crystallographic planes. Using molecular dynamics simulations, we show that upon adsorption the peptides adopt a predictable conformation. We compute the binding energies of the amino acids constituting two adhesion peptides for Pt, S7, and T7 and demonstrate that peptides' surface recognition behavior that makes them unique among populations originates from differential adsorption of their building blocks. We find that the degree of peptide binding is mainly due to polar amino acids and the molecular architecture of the peptides close to the Pt facets. Our analysis is a first step in the prediction of enhanced affinity between inorganic materials and a peptides, toward the synthesis of novel nanomaterials with programmable shape, structure, and properties.
|
|
|
Changes induced by peripheral nerve injury in the morphology and nanomechanics of sensory neurons.
Auteur(s): Benzina Wafa, Szabo Vivien, Lucas Olivier, Saab Marie-Belle, Cloitre T., Scamps Frédérique, Gergely C., Martin Fernandez M.
(Article) Publié:
Journal Of Biomedical Optics, vol. 18 p.106014 (2013)
Texte intégral en Openaccess :
Ref HAL: hal-00903504_v1
DOI: 10.1117/1.JBO.18.10.106014
WoS: 000326563000046
Exporter : BibTex | endNote
6 Citations
Résumé: Peripheral nerve injury in vivo promotes a regenerative growth in vitro characterized by an improved neurite regrowth. Knowledge of the conditioning injury effects on both morphology and mechanical properties of live sensory neurons could be instrumental to understand the cellular and molecular mechanisms leading to this regenerative growth. In the present study, we use differential interference contrast microscopy, fluorescence micros- copy, and atomic force microscopy (AFM) to show that conditioned axotomy, induced by sciatic nerve injury, does not increase somatic size of sensory neurons from adult mice lumbar dorsal root ganglia but promotes the appear- ance of longer and larger neurites and growth cones. AFM on live neurons is also employed to investigate changes in morphology and membrane mechanical properties of somas of conditioned neurons following sciatic nerve injury. Mechanical analysis of the soma allows distinguishing neurons having a regenerative growth from control ones, although they show similar shapes and sizes.
|
|
|
Porous silicon scaffolds for stem cells growth and osteodifferentiation.
Auteur(s): Collart Dutilleul Pierre-Yves, Deville De Périère D., Cuisinier Frédéric J. G., Cunin Frédérique, Gergely C.
Chapître d'ouvrage: Porous Silicon For Biomedical Applications., vol. p.486-506 (2013)
|
|
|
Nitride devices and their bio-functionalization for biosensing applications.
Auteur(s): Gergely C.
Chapître d'ouvrage: Iii-Nitride Semiconductors And Their Modern Devices., vol. p.505-518 (2013)
|
|
|
Light energy conversion by phtosynthetic reaction center-hybrid nanostructures
Auteur(s): Hadju Kata, Marquez-Leon J., Cloitre T., Martin Fernandez M., Szabo T., Agarwal Vivechana, Palestino Gabriela, Gergely C., Zimanyi Laszlo, Nagy Laszlo
Conference: XXII International Materials Research Congress (Cancun, MX, 2013-08-11)
|
|
|
Optical and electronic properties of biomolecule-functionalized porous silicon photonic structures
Auteur(s): Hadju Kata, Marquez-Leon J., Cloitre T., Martin Fernandez M., Agarwal Vivechana, Nagy Laszlo, Palestino Gabriela, Gergely C., Zimanyi Laszlo
Conférence invité: XXII International Materials Research Congress (Cancun, MX, 2013-08-11)
|
|
|
A COMPREHENSIVE STUDY ON POROUS SILICON MICROCAVITIES' FUNCTIONALIZATION WITH PEPTIDES FOR BIOSENSING
Auteur(s): Ramakrishnan S., Estephan Elias, Martin Fernandez M., Cloitre T., Hadju Kata, Nagy Laszlo, Zimanyi Laszlo, Palestino Gabriela, Agarwal Vivechana, Gergely C.
Conférence invité: XXII International Materials Research Congress (Cancun, MX, 2013-08-11)
|