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- DNA twist and bending govern the denaturation bubble slow dynamics hal link

Auteur(s): Manghi Manoel, Dasanna Anil, Destainville Nicolas, Palmeri J.

(Affiches/Poster) Soft Matter 2013 (Rome, IT), 2013-09-15


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Résumé:

The closure of long equilibrated denaturation bubbles in DNA is studied using Brownian dynamics simulations. A minimal mesoscopic model is used where the double helix is made of two interacting bead-spring freely rotating strands, with a nonzero torsional modulus in the duplex state.