Laboratoire Charles Coulomb UMR 5221 CNRS/UM2 (L2C)

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Photo de WALTER Jean-charles
WALTER Jean-Charles      
Fonction : Chercheur
Organisme : CNRS
Chargé de Recherche
(HDR)
Encadre la thèse de : CHEVALIER C.,
Autre(s) thème(s) de recherche ou rattachement(s) :
 - Physique théorique des systèmes biologiques
 - Physique Non-linéaire
jean-charles.walter_AT_umontpellier.fr
Bureau: 36, Etg: 3, Bât: 21 - Site : Campus Triolet

Administration Locale:
  • Membre du conseil du laboratoire
Activités de Recherche:     
I am a theoretical physicist interested in the description of biological processes. The functioning of a cell requires the coordinated motion and positioning of various actors among which biopolymers (e.g., RNA & DNA), proteins and molecular motors. Their interactions - and subsequent reaction and motion - can be described with a physical approach. My current projects include: (i) the bacterial DNA organization and segregation (with LMGM, Toulouse & TIMC, Grenoble); (ii) the translation of messenger RNA by ribosomes in human cells (with IGF & LIRMM, Montpellier); (iii) the spatial organization of chromosomes and epigenetic regulation in Drosophila via polycomb domains (with CBS & IGH, Montpellier); (iv) the bacterial flagella motion of E. coli through the recruitment of molecular motors (with CBS, Montpellier).

Co-organizer (with I. Junier and J-Y. Bouet) of "Bacterial DNA supercoiling @ Sète" since 2019 in Sète, France.

Reach out science: book on science for children "Mon amie Alphée" with Alexandra Jeuillard & Camille Saulnier to appear at Encre de Siagne Editions in early 2023.

We have a funding for a Master 2 project on the modeling of the interactions fungus-plant-microbiote in collaboration with biologists. Feel free to contact us!
Domaines de Recherche:
  • Physique/Physique/Biophysique
HDR
+ Modeling the formation and positioning of intracellular macromolecular assemblies: Application to bacterial DNA segregation hal link

Auteur(s): Walter J.-C.

(H.D.R.) , 2020
Texte intégral en Openaccess : fichier pdf

Dernieres productions scientifiques :
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+ Physical modeling of ribosomes along messenger RNA: estimating kinetic rates from ribosome profiling experiments with a ballistic model doi link

Auteur(s): Chevalier C., Dorignac J., Ibrahim Yahaya, Choquet Armelle, David Alexandre, Ripoll Julie, Rivals Eric, Geniet F., Walliser N.-O., Palmeri J., Parmeggiani A.(Corresp.), Walter J.-C.(Corresp.)

(Document sans référence bibliographique) 2022-09-01
Texte intégral en Openaccess : arxiv

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+ Physical modeling of ribosomes along mRNA: estimating kinetic rates from ribosome profiling experiments hal link

Auteur(s): Walter J.-C.

Conférence invité: RNA Club (Montpellier, FR, 2022-10-12)

Texte intégral en Openaccess : fichier pdf

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+ The bacterial DNA segregation complexes ParBS display a twofold phase separation hal link

Auteur(s): Walter J.-C.

Conference: International Physics of Living Systems ’22 (Montpellier, FR, 2022-05-31)

Texte intégral en Openaccess : fichier pdf

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+ Physical Modeling of Translation with a Ballistic Model: Application to the Estimation of the Kinetic Parameters from Ribosome Sequencing Experiments hal link

Auteur(s): Chevalier C., Dorignac J., Ibrahim Yahaya, Choquet Armelle, David Alexandre, Ripoll Julie, Rivals Eric, Geniet F., Walliser N.-O., Palmeri J., Parmeggiani A., Walter J.-C.

(Affiches/Poster) Annual Meeting of the International Physics of Living Systems (iPoLS) Network (Montpellier, FR), 2022-05-31
Texte intégral en Openaccess : fichier pdf

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+ Multiplexed chromatin imaging reveals predominantly pairwise long-range coordination between Drosophila Polycomb genes doi link

Auteur(s): Gurgo Julian, Walter J.-C., Fiche Jean-Bernard, Houbron Christophe, Schaeffer Marie, Cavalli Giacomo, Bantignies Frédéric, Nollmann Marcelo

(Document sans référence bibliographique) 2022-05-30
Texte intégral en Openaccess : openaccess

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