Laboratoire Charles Coulomb UMR 5221 CNRS/UM2 (L2C)


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Photo de WALTER Jean-charles
WALTER Jean-Charles      
Fonction : Chercheur
Organisme : CNRS
Chargé de Recherche
Encadre la thèse de : CHEVALIER C.,
Autre(s) thème(s) de recherche ou rattachement(s) :
 - Physique théorique des systèmes biologiques
 - Physique Non-linéaire
Bureau: 51, Etg: 1, Bât: 13 - Site : Campus Triolet

Curriculum Vitae:     
2017-present: Researcher at L2C, CNRS, Montpellier
2013-2017: Postdoc, L2C, Université de Montpellier
2012: Postdoc, Lorentz Institute, University of Leiden, The Netherlands
2009-2011: Postdoc, Institute for Theoretical Physics, KULeuven
2009: PhD, Université Henri Poincaré, Nancy, France
Activités de Recherche:     
I am a theoretical physicist interested in the description of biological processes. The functioning of a cell requires the coordinated motion and positioning of various actors among which biopolymers (e.g., RNA and DNA), proteins and molecular motors. Their interactions - and subsequent reaction and motion - can be described with a physical approach. My current projects include: (i) the bacterial DNA organization and segregation (with LMGM and TIMC); (ii) the translation of messenger RNA by ribosomes in human cells (with IGF and LIRMM); (iii) the spatial organization of chromosomes and epigenetic regulation in Drosophila via polycomb domains (with CBS & IGH); (iv) the bacterial flagella motion through the recruitment of molecular motors (with CBS).

Co-organizer (with I. Junier and J-Y. Bouet) of "Bacterial DNA supercoiling @ Sète" in '19, '20 and '21 in Sète, France.

Reach out science: book on science for children "Mon amie Bergamote" with Alexandra Jeuillard & Camille Saulnier.
Domaines de Recherche:
  • Physique/Physique/Biophysique
+ Modeling the formation and positioning of intracellular macromolecular assemblies: Application to bacterial DNA segregation hal link

Auteur(s): Walter J.-C.

(H.D.R.) , 2020
Texte intégral en Openaccess : fichier pdf

Dernieres productions scientifiques :
+ Genomic physics: biophysical modeling confronted to genomic data

Auteur(s): Walter J.-C.(Corresp.)

Conférence invité: Labex NUMEV Days (Montpellier, FR, 2021-11-09)

+ Relaxation time asymmetry in stator dynamics of the bacterial flagellar motor doi link

Auteur(s): Perez-Carrasco Ruben, Franco-Oñate M.-J., Walter J.-C., Dorignac J., Geniet F., Palmeri J., Parmeggiani A., Walliser N.-O., Nord Ashley

(Document sans référence bibliographique)
Texte intégral en Openaccess : openaccess

+ Modelling the effect of ribosome mobility on the rate of protein synthesis (vol 44, 19, 2021) doi link

Auteur(s): Dauloudet O., Neri I., Walter J.-C., Dorignac J., Geniet F., Parmeggiani A.

(Article) Publié: European Physical Journal E, vol. 44 p.60 (2021)
Texte intégral en Openaccess : openaccess

+ Physical modeling of the ParBS complex: insight into Liquid-Liquid Phase Separation hal link

Auteur(s): Walter J.-C.(Corresp.)

Conférence invité: BioPhyChrom 2021 (The biology and physics of bacterial chromosome organization) (Leiden, NL, 2021-04-29)

Texte intégral en Openaccess : fichier pdf

+ Supercoiled DNA and non-equilibrium formation of protein complexes: A quantitative model of the nucleoprotein ParBS partition complex doi link

Auteur(s): Walter J.-C.(Corresp.), Lepage Thibaut, Dorignac J., Geniet F., Parmeggiani A., Palmeri J., Bouet Jean-Yves, Junier Ivan

(Article) Publié: Plos Computational Biology, vol. 14 p.e1008869 (2021)
Texte intégral en Openaccess : openaccess