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Research internship – 2024-2025 Master 2 level Detection of individual biomolecules transported through a carbon nanotube using nanopore sensing
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Research project
With their unique electronic properties and unique inner channel, carbon nanotubes make both excellent electronic sensors and excellent nanofluidic channels although these two aspects have rarely been combined. The aim of the project is to investigate the coupling between the transport of ions in the nanotube channel and the transport of electrons in the nanotube wall, in view of developing ultrasensitive analysis methods of single molecules based on both electronic and ionic signals.
More precisely, the project will include the study of electro-ionic devices incorporating individual carbon nanotubes, which are fabricated in our team. The master intern will learn how to make precise measurements of both ionic and electronic currents (pA) using a dedicated low-current measurement setup, and study how they are coupled as a function of the experimental parameters (pH, salt concentration, applied voltages…). The detection of small model biomolecules (nucleotides, amino acids, glucose) in NTCs will then be studied through coupled ionic and electrical measurements.
The research will be based at Laboratory Charles Coulomb, a joint research centre of the University of Montpellier and CNRS, which has a strong expertise in the fabrication, the characterization and the electrical, optical and nanofluidic studies of carbon nanotubes.
The recruited M2 intern will work within a project team of six people (professors, CNRS researcher and engineers).
A PhD continuation of the project is envisioned.
Sought profile
We are looking for a master 2 student in physics, chemistry, biophysics or materials science motivated by the pursuit of a PhD thesis. A strong interest for the nanofluidic and/or electronic properties nanostructures and/or the development of novel biosensing methods is important. Candidates demonstrating high personal motivation, experimental rigor, a taste for experimental work and good communication skills in English are strongly encouraged to apply.
Application date : from now and until selection of the candidate
Starting date : between February 2025 and March 2025
Internship duration : 5-6 months
Supervisors :
Vincent Jourdain
Adrien Noury
François Henn
Website of Laboratoire Charles Coulomb
Webpage of the University of Montpellier
Application details
The candidate must send :
- - a personalized motivation letter detailing his/her interest for the project and his/her aptitudes for leading the proposed research,
- - a detailed CV describing his/her past research achievements,
- - the contact details of 1-2 reference persons.
Incomplete applications will not be considered.
